How Exatype Works


Quality Control

Next-generation sequencing reads are trimmed of low-quality bases, and short or otherwise inferior reads are discarded.


Reference Mapping

Examap, a novel, codon-aware reference mapping tool, uses an assembly-free approach to map sequence reads to one or more reference sequences while considering both sequencing error and true diversity.


Mutation Calling

Mutations are called in each individual read. The Examap algorithm allows mutations to be called with >99% per-read accuracy.


Resistance Testing

Relevant genes and mutations, if present at sufficient prevalence, are analysed using accurate drug resistance testing algorithms.